Anti-NEDD4L Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

10373-984EA 776.19 USD
Anti-NEDD4L Rabbit Polyclonal Antibody (Cy7®)
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: NEDD4L
Clonality: Polyclonal
Conjugation: Cy7®
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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