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Anti-CYLD Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss
Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Has endodeubiquitinase activity. Plays an important role in the regulation of pathways leading to NF-kappa-B activation. Contributes to the regulation of cell survival, proliferation and differentiation via its effects on NF-kappa-B activation. Negative regulator of Wnt signaling. Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules. Plays a role in the regulation of microtubule dynamics, and thereby contributes to the regulation of cell proliferation, cell polarization, cell migration, and angiogenesis. Required for normal cell cycle progress and normal cytokinesis. Inhibits nuclear translocation of NF-kappa-B. Plays a role in the regulation of inflammation and the innate immune response, via its effects on NF-kappa-B activation. Dispensable for the maturation of intrathymic natural killer cells, but required for the continued survival of immature natural killer cells. Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity).

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: CYLD
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype:
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-3080R-HRP 10350-990 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CYLD
Antigen Name Cylindromatosis 1 (turban tumor syndrome)
Reactivity Human, Rat, Mouse
Conjugation HRP (Horseradish Peroxidase)
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms SBS, EAC, MFT, BRSS, CYLDI, CDMT, MFT1, USPL2, TEM, CYLD1
Gene ID 1540
Modification phospho-Ser418
Concentration 1 μg/μl
Cross Adsorption No
Immunogen 390-440/956
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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