Anti-HDAC4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

BS-3073R-A647

10350-824EA 776.19 USD

10350-824

Anti-HDAC4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Antibodies

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: HDAC4
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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