Anti-LRP5 + LRP6 Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

BS-2905R-CY3
10348-206EA 811.1 USD
10348-206
Anti-LRP5 + LRP6 Rabbit Polyclonal Antibody (Cy3®)
Antibodies
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: LRP5 + LRP6
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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