Anti-ZAK/HCCS4 Rabbit Polyclonal Antibody (Cy5.5®)

13546R-CY5.5
10227-282EA 559.62 USD
10227-282
Anti-ZAK/HCCS4 Rabbit Polyclonal Antibody (Cy5.5®)
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ZAK/HCCS4
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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