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Anti-C5AR2 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
Anaphylatoxin, a chemotactic and inflammatory peptide, is a receptor for C5a anaphylatoxin chemotactic receptor (C5L2), also designated G protein-coupled receptor 77. C5L2 is an integral membrane protein that belongs to the Gprotein-coupled receptor 1 family. C5L2 weakly couples to Gi-mediated signaling pathways and is widely expressed in the hippocampus, hypothalamus, pons, frontal cortex and liver. It is coexpressed with the C5a receptor (C5AR) on polymorphonuclear neutrophils and may modulate the activity of C5AR. The function of the C5a receptors, particularly that of C5L2, is still unclear. Research suggests that C5L2 may be required for the in vitro release of high mobility group box 1 protein (HMGB1).

Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200

Type: Primary
Antigen: C5AR2
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-13506R-CY5 10299-640 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol C5AR2
Antigen Name Complement Component 5a receptor 2
Reactivity Human
Conjugation Cy5®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Flow Cytometry Yes
Antigen Synonyms C5L2, GPR77, GPF77
Gene ID 27202
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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