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Anti-GOT1L1 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss
GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GOT1L1
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-13494R-CY7 10299-310 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol GOT1L1
Antigen Name Glutamic-oxaloacetic Transaminase 1-like 1
Reactivity Mouse, Human, Rat
Conjugation Cy7®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms AATC2_HUMAN, Transaminase A-like protein 1., cytoplasmic 2, GOT1L1, Putative aspartate aminotransferase, Glutamic oxaloacetic transaminase 1 like 1, Glutamate oxaloacetate transaminase 1-like protein 1
Gene ID 137362
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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