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Anti-GNL3L Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss
GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GNL3L
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-13472R-A350 10298-636 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol GNL3L
Antigen Name Guanine Nucleotide Binding Protein-like 3 (nucleolar)-like
Reactivity Human, Mouse, Rat
Conjugation Alexa Fluor® 350
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms novel GTPase, OTTHUMP00000023374., GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 nucleolar-like
Gene ID 54552
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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