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Anti-ACAN Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
The large chondroitin sulfate proteoglycan, aggrecan, is the predominant proteoglycan present in cartilage. Aggrecan is a member of the chondroitin sulphate proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification. Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage. Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family. In the adult brain, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ACAN
Clonality: Polyclonal
Conjugation: Cy5.5®
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL 11655R-CY5.5 10224-554 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol ACAN
Antigen Name Aggrecan
Reactivity Mouse, Rat, Human
Conjugation Cy5.5®
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen Synonyms Chondroitin sulfate proteoglycan 1, MSK16, Chondroitin sulfate proteoglycan core protein 1, CSPG1, CSPCP, large aggregating proteoglycan, AGC1, aggrecan 1, aggrecan, AGCAN, SEDK, aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPGCP
Concentration 1 μg/μl
Cross Adsorption No
Immunogen 180-230/2415
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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