Anti-FISH Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

BS-11645R-CY3
10260-498EA 810.85 USD
10260-498
Anti-FISH Rabbit Polyclonal Antibody (Cy3®)
Antibodies
Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FISH
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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