Anti-APP Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss

BS-0112M-HRP
10231-312EA 776.17 USD
10231-312
Anti-APP Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antibodies
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: APP
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human, Rat, Rabbit
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