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Anti-GSK3B Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss

Glycogen synthase kinase-3 beta (GSK3Beta) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Belongs to the Ser/Thr protein kinase family.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: GSK-3 Beta
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-0028M-HRP 10229-594 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name Glycogen Synthase Kinase 3 beta
Antigen Symbol GSK3B
Antigen Synonyms Factor A, GSK3B, EC 2.7.11.26, GSK-3 beta, GSK-3 beta Factor A
Clonality Polyclonal
Concentration 1 μg/μl
Conjugation HRP (Horseradish Peroxidase)
Cross Adsorption No
Form liquid
Gene ID 2932
Host Mouse
ImmunoChemistry Yes
Isotype IgG
Purification Purified by Protein A
Reactivity Human, Rat
Shipping Temperature 4°C
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage Temperature Store at 4°C for 12 months
Western Blot Yes
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