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Anti-KIAA0141 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals

600-401-AU8

10802-434EA 518.29 USD

10802-434

Anti-KIAA0141 Rabbit Polyclonal Antibody

Antibodies

DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-a and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-a, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

Recommended Dilutions: ELISA: 1:10,000; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: KIAA0141
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Rat

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