Anti-CD209 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
600-401-AT8
10801-106EA 518.29 USD
10801-106
Anti-CD209 Rabbit Polyclonal Antibody
Antibodies
Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 10 ?g/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1-2 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CD209
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype: IgG1
Reactivity: Human
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