Anti-DAPK2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
600-401-AS5
10800-978EA 518.29 USD
10800-978
Anti-DAPK2 Rabbit Polyclonal Antibody
Antibodies
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFN-gamma induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopicly expressed DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: 2 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: DAPK2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat
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