Anti-CIDEA Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
600-401-AK4
10800-822EA 518.29 USD
10800-822
Anti-CIDEA Rabbit Polyclonal Antibody
Antibodies
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.

Recommended Dilutions: ELISA: 1:5,000; Immunohistochemsitry: 5 µg/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 0.5 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CIDEA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity:
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR