CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
Recommended Dilutions: ELISA: 1:5000-1:10000; Immunohistochemsitry: 5 µg/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 0.5-1 ?g/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: MTUS2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse