Anti-CARM1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
600-401-AB7
10800-528EA 518.29 USD
10800-528
Anti-CARM1 Rabbit Polyclonal Antibody
Antibodies
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunofluorescence Microscopy: User Optimized; Western Blot: 1-2 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CARM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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