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Anti-BCL2L1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals

Anti-BCL2L1 Rabbit polyclonal antibody

Anti-BCL2L1 Rabbit polyclonal antibody

200-401-Z50

10802-044EA 518.29 USD

10802-044

Anti-BCL2L1 Rabbit Polyclonal Antibody

Antibodies

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Western Blot: 1 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: BCL2L1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: Human

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