Anti-BNIP3L Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals
200-401-G87
10800-656EA 518.29 USD
10800-656
Anti-BNIP3L Rabbit Polyclonal Antibody
Antibodies
CCR5 antibody detects a G coupled -protein receptor. Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes. Anti-CCR5 antibodies are ideal for investigators involved in Cytokines and Growth Factors and Infectious Disease research.

Recommended Dilutions: Immunohistochemsitry: 20 ug/mL; Western Blot: 1:1000-1:2000; contains 0.01% (w/v) Sodium Azide

Type: Primary
Antigen: BNIP3L
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype:
Reactivity: Human
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