Anti-GFAP Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: S206A-8]

Supplier: Rockland Immunochemicals
200-308-W55
10802-970EA 538.68 USD
10802-970
Anti-GFAP Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: S206A-8]
Antibodies
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. Anti-GFAP is ideal for investigators involved in Neuroscience Research, including Alexander Disease, Oligodendroglioma, Cytoskleton Remolding Neurofilaments and PIP3/AKT Signaling.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: User Optimized; Western Blot: 1:1000; 0.1% (w/v) Sodium Azide

Type: Primary
Antigen: GFAP
Clonality: Monoclonal
Clone: S206A-8
Conjugation: RPE (R-Phycoerythrin)
Epitope: C-terminal
Host: Mouse
Isotype:
Reactivity: Human, Rat, Mouse
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