Anti-TUBA1B Mouse Monoclonal Antibody [clone: 17H11.F10]

Supplier: Rockland Immunochemicals
200-301-880S 200-301-880S
10799-984EA 147.5 USD
10799-984 CA10799-984
Anti-TUBA1B Mouse Monoclonal Antibody [clone: 17H11.F10]
Antibodies
Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.  This antibody makes an excellent loading control.

Recommended Dilutions: ELISA: 1:300,000; Immunohistochemsitry: 2.5 µg/mL; Immunofluorescence Microscopy: 0.1 µg/mL; Western Blot: 1:1,000; contains 0.01% (w/v) Sodium Azide

Type: Control
Antigen: TUBA1B
Clonality: Monoclonal
Clone: 17H11.F10
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human, Mouse, Rat. Chicken, Bovine
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