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Anti-CDC73 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemicals

100-301-V39

10801-092EA 464.71 USD

10801-092

Anti-CDC73 Rabbit Polyclonal Antibody

Cdc73 is a tumor suppressor probably involved in transcriptional and posttranscriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/ PRAD1 expression. Anti-dCdc73 Antibody is ideal for research in Gene Expression, Transcription, Epigenetics, Cell Cycle Control and Cancer.

Recommended Dilutions: ChIP: 1-5 ?g/ChIP; Immunoprecipitation: 12 ?g per IP; Western Blot: 1:1,000; contains 0.05% (w/v) Sodium Azide

Type: Primary
Antigen: CDC73
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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