Anti-CD19 Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)) [clone: SJ25C1]

Supplier: Tonbo Biosciences
67-0198-T100 67-0198-T500 67-0198-T025
10753-830EA 1492.39 USD
10753-830 10753-826 10753-828
Anti-CD19 Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)) [clone: SJ25C1]
Antibodies
The SJ25C1 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 (CR2), CD81 (TAPA-1) and CD225 (Leu13), in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. Upon activation and tyrosine phosphorylation, the CD19 molecule can provide an anchor for cytoplasmic signaling proteins such as GRB2, SOS or PLCG2. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

Type: Primary
Antigen: CD19
Clonality: Monoclonal
Clone: SJ25C1
Conjugation: PerCP (Peridinin-Chlorophyll Protein Complex)
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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