Anti-PMAIP1 Rabbit Polyclonal Antibody

Supplier: BioVision
3665-100
10004-482EA 285.6 USD
10004-482
Anti-PMAIP1 Rabbit Polyclonal Antibody
Noxa is a BH3-only member of the Bcl-2 family. Expression of Noxa gene involves direct activation of its promotor by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53-deficient thymocytes. Coimmunoprecipitation data sμggest that Noxa protein may interact with proteins belonging to the Bcl-2 family, such as Bcl-xL and Mcl-1. Blocking the endogenous Noxa induction results in the suppression of apoptosis. These sμggest Noxa may represent a candidate mediator of p53-induced apoptosis.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: PMAIP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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