Anti-Rab5 Rabbit Polyclonal Antibody

Supplier: BioVision
3483-100
10004-076EA 309.39 USD
10004-076
Anti-Rab5 Rabbit Polyclonal Antibody
Rab5 is a 24 kDa GTP-binding protein that is localized to the cytoplasmic side of the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5 is believed to regulate vesicle fusion throμgh a cycle of GDP/GTP exchange and GTP hydrolysis. The different guanine nucleotide binding states of rab5 is postulated to affect its ability to associate or dissociate with membranes during endocytotic membrane traffic. Its GTP-bound form, which represents the active form of Rab5, associates with membrane and regulates vesicle docking and fusion.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; immunoprecipitation and immunhistochemistry

Type: Primary
Antigen: Rab5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Monkey, Bovine
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