Anti-CASP8 Rabbit Polyclonal Antibody

Supplier: BioVision
3259-100
10005-278EA 309.39 USD
10005-278
Anti-CASP8 Rabbit Polyclonal Antibody
Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase-8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase-8 is able to cleave and activate downstream caspases, such as caspase-3, -6, -7 and a death agonist member of the Bcl-2/Bcl-xL family, Bid, leading to apoptosis.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml

Type: Primary
Antigen: CASP8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR