Anti-PAK1 Rabbit Polyclonal Antibody

Supplier: BioVision
3248-100
10003-676EA 309.39 USD
10003-676
Anti-PAK1 Rabbit Polyclonal Antibody
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; Immunoprecipitation: 10-20 µg/ml

Type: Primary
Antigen: PAK1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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