Anti-CASP1 Rabbit Polyclonal Antibody

Supplier: BioVision
AB286125-100UG
10003-224EA 646.78 USD
10003-224
Anti-CASP1 Rabbit Polyclonal Antibody
Antibodies
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.

Recommended Dilutions: Western Blot: 0.5-4 µg/ml; Immunoprecipitation: 4-8 µg/ml; Iimmunofluorescence: 10-20 µg/ml

Type: Primary
Antigen: CASP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat
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