Human Recombinant BMP-14 GDF-5 (from E. coli)

Supplier: BioVision
AB52315-50
10191-944EA 288.55 USD
10191-944
Human Recombinant BMP-14 GDF-5 (from E. coli)
Proteins and Peptides
>98% Pure active Recombinant human BMP-14 (GDF-5/CDMP-1).

The ED₅₀ as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-2 µg/ml.

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.
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