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Anti-PARP p85 Fragment Rabbit Polyclonal Antibody

Supplier: Promega Corporation
G7341
Specific in situ marker of apoptosis recognizing the p85 fragment of PARP resulting from caspase-3 cleavage.

  • A Specific In Situ Marker of Apoptosis
  • Specifically detects PARP p85 fragment in human, rat and bovine cells and tissues

Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme involved in DNA repair, is a well known substrate for caspase-3 cleavage during apoptosis. Anti-PARP p85 Fragment pAb is a rabbit polyclonal antibody specific for the p85 fragment of PARP that results from caspase cleavage of the 116kDa intact molecule and thus provides an in situ marker for apoptosis. The antibody is affinity-purified using a peptide that corresponds to a region of the p85 fragment of PARP. The PARP immunogen is a synthetic peptide, gly-val-asp-glu-val-ala-lys (GVDEVAK), representing the N-terminus of the large C-terminal fragment of human PARP that results from caspase-3 cleavage. Each batch of antibody is quality assurance tested for use in immunostaining applications and contains sufficient antibody for 50 immunocytochemical reactions at the suggested working dilution of 1:100.

It is quality assurance tested for use in immunostaining applications and contains sufficient antibody for 50 immunocytochemical reactions at the suggested working dilution of 1:100.

Type:
Antigen: PARP p85 Fragment
Clonality: Polyclonal
Clone:
Conjugation:
Epitope: C-terminal, N-terminal
Host: Rabbit
Isotype:
Reactivity: Human, Rat, Bovine cells and Tissues




 

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Size Storage Temperature Supplier No. VWR Catalog Number Unit Price Quantity
50 μl -30°C to -10°C G7341 PAG7341 Each (50µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol PARP1
Antigen Name Poly (ADP-ribose) polymerase 1
Reactivity Bovine, Human, Rat
Clonality Polyclonal
Host Rabbit
Western Blot Yes
Antigen Synonyms pADPRT-1, ADPRT, PARP1, PARP-1, ADPRT1, PARP, PPOL
Epitope C-terminal, N-terminal
Molecular Weight 116 kDa
Tested Applications Immunohistochemistry
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