Anti-CD274 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: 10F.9G2]

Supplier: ProSci
76-960
10765-822EA 448.21 USD
10765-822
Anti-CD274 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: 10F.9G2]
Antibodies
The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.

Type: Primary
Antigen: CD274
Clonality: Monoclonal
Clone: 10F.9G2
Conjugation: PE
Epitope:
Host: Rat
Isotype: Rat IgG2b, kappa
Reactivity: Mouse
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