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Anti-CD3E Hamster Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 145-2C11]

Supplier: Prosci
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa epsilon chain of the TCR complex. Together with the gamma and delta subunits of CD3, the epsilon subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the epsilon chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.

Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: 145-2C11
Conjugation: PE (Phycoerythrin)-Cy7®
Host: Hamster
Isotype: IgG



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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 µg 76-276 10764-304 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol CD3E
Antigen Name CD3 Molecule Epsilon
Reactivity Mouse
Conjugation PE (Phycoerythrin)-Cy7®
Clonality Monoclonal
Antibody Type Primary
Clone 145-2C11
Host Hamster
Isotype IgG
Flow Cytometry Yes
Antigen Synonyms T-cell surface glycoprotein CD3 epsilon chain, TCRE, FLJ18683, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e antigen, epsilon subunit of T3, CD3-epsilon, epsilon polypeptide TiT3 complex, T-cell antigen receptor complex
Concentration 0.2 mg/ml
Cross Adsorption No
Purification purified utilizing affinity chromatography and unreacted dye was removed from the product.
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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