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Anti-Ctla4 Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: UC10-4F10-11]

Supplier: Prosci
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.

Type: Primary
Antigen: Ctla4
Clonality: Monoclonal
Clone: UC10-4F10-11
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Hamster
Isotype:
Reactivity:




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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 µg 76-856 10764-956 Each Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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SPECIFICATIONS

Antigen Symbol CTLA4
Antigen Name Cytotoxic T-lymphocyte-Associated Protein 4
Reactivity Mouse
Conjugation APC (Allophycocyanin)
Clonality Monoclonal
Antibody Type Primary
Clone UC10-4F10-11
Host Hamster
Isotype IgG
Flow Cytometry Yes
Antigen Synonyms CD, IDDM12, CTLA-4, GSE, ALPS5, CD152, CELIAC3, GRD4, cytotoxic T-lymphocyte associated protein 4
Concentration 0.2 mg/ml
Cross Adsorption No
Purification purified utilizing affinity chromatography and unreacted dye was removed from the product.
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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