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Anti-TNF Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: MAb11]

Supplier: ProSci

77-182

10765-856EA 572.84 USD

10765-856

Anti-TNF Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: MAb11]

Antibodies

The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha (TNF-alpha), a 157 amino acid non-glycosylated protein. TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. The MAB11 antibody was generated from recombinant human TNF and is reported to be a neutralizing antibody.

Type: Primary
Antigen: TNF
Clonality: Monoclonal
Clone: MAb11
Conjugation: FITC
Epitope:
Host: Mouse
Isotype: Mouse IgG1, kappa
Reactivity: Human

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