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Anti-CD86 Rat Monoclonal Antibody [clone: GL-1 (GL1)]

Supplier: Prosci
The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity. The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibits the T-cells stimulation by antigen-presenting cells. Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes.

Type: Primary
Antigen: CD86
Clonality: Monoclonal
Clone: GL-1 (GL1)
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg 76-597 10764-702 Each Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CD86
Antigen Name CD86 molecule
Reactivity Mouse
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone GL-1 (GL1)
Host Rat
Isotype IgG2a kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen Synonyms B70, ETC-1, TS/A-2, B7-2, Cd28l2, Ly58, MB7-2, MB7, B7.2, Ly-58, B7, CLS1
Concentration 0.5 mg/ml
Cross Adsorption No
Purification purified utilizing affinity chromatography and unreacted dye was removed from the product.
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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