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Anti-CD80 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 2D10.4]

Supplier: Prosci
The 2D10.4 antibody reacts with human CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type: Primary
Antigen: CD80
Clonality: Monoclonal
Clone: 2D10.4
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 Tests 76-038 10766-176 Each Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CD80
Antigen Name CD80 molecule
Reactivity Human
Conjugation PE (Phycoerythrin)
Clonality Monoclonal
Antibody Type Primary
Clone 2D10.4
Host Mouse
Isotype IgG1 kappa
Flow Cytometry Yes
Antigen Synonyms B71, MIC17, Cd28l, Ly-53, Ly53, Cluster of Differentiation 80, TSA1
Concentration 5 uL (1 ug) / test
Cross Adsorption No
Purification purified utilizing affinity chromatography and unreacted dye was removed from the product.
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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