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Anti-CD44 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: IM7]

Supplier: Prosci
The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 µg 76-415 10766-418 Each Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CD44
Antigen Name Cluster of Differentiation 44 antigen
Reactivity Human, Mouse
Conjugation FITC (Fluorescein Isothiocyanate)
Clonality Monoclonal
Antibody Type Primary
Clone IM7
Host Rat
Isotype IgG2b kappa
Flow Cytometry Yes
Antigen Synonyms HCAM, CSPG8, LHR, MIC4, ECMR-III, IN, CDW44, Pgp1, HUTCH-I, MC56, MDU2, HCELL, MDU3
Concentration 0.5 mg/ml
Cross Adsorption No
Purification purified utilizing affinity chromatography and unreacted dye was removed from the product.
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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