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Anti-CD44 Rat Monoclonal Antibody [clone: IM7]

Supplier: Prosci
The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: Unconjugated
Host: Rat
Isotype: IgG2b kappa

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Size Supplier No. VWR Catalog Number Unit Price Quantity
500 µg 76-411 10766-410 Each Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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Antigen Symbol CD44
Antigen Name Cluster of Differentiation 44 antigen
Reactivity Mouse, Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone IM7
Host Rat
Isotype IgG2b kappa
Flow Cytometry Yes
Antigen Synonyms HCAM, MDU3, MIC4, CSPG8, Pgp1, HUTCH-I, CDW44, HCELL, MC56, MDU2, LHR, ECMR-III, IN
Concentration 1 mg/ml
Format purified antibody
Cross Adsorption No
Form liquid
Storage Buffer Phosphate-buffered aqueous solution, ph7.2.
Storage Temperature The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Shipping Temperature -20°C
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