Anti-ITGA4 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: DATK32]

Supplier: ProSci
77-138
10765-752EA 448.24 USD
10765-752
Anti-ITGA4 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: DATK32]
Antibodies
The DATK32 monoclonal antibody specifically reacts with an epitoPE of the Mouse alpha-4-beta-7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha-4 and the 130 kDa beta-7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha-4-beta-7 integrin heterodimer. alpha-4-beta-7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the alpha-4-beta-7 induces the alpha-4-beta-7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.

Type: Primary
Antigen: Itga4
Clonality: Monoclonal
Clone: DATK32
Conjugation: PE
Epitope:
Host: Rat
Isotype: Rat IgG2a, kappa
Reactivity: Mouse
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