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Anti-PCBP4 Rabbit Polyclonal Antibody

Supplier: ProSci

Western blot analysis of MCG10 in HeLa cell lysate with MCG10 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.

Immunocytochemistry of MCG10 in HeLa cells with MCG10 antibody at 1 µg/ml.

Immunofluorescence of MCG10 in Hela cells with MCG10 antibody at 20 µg/ml.

Western blot analysis of MCG10 in HeLa cell lysate with MCG10 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.

Immunocytochemistry of MCG10 in HeLa cells with MCG10 antibody at 1 µg/ml.

Immunofluorescence of MCG10 in Hela cells with MCG10 antibody at 20 µg/ml.

2479_S

10749-462EA 179.85 USD

10749-462

Anti-PCBP4 Rabbit Polyclonal Antibody

Antibodies

MCG10 Antibody: MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

Type: Primary
Antigen: PCBP4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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