Puromycin dihydrochloride ≥98% (by HPLC)
Supplier: BioVision
Puromycin Dihydrochloride is a nucleoside antibiotic
- White to off-white powder
Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/mL, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/mL.
It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells.
Soluble in Water (50 mg/mL)
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