Keep my session open?
Ending In 
Your shopping session has expired.
Your session has expired. For your security, we have logged you out.
Would you like to log in again?

Anti-HES1 Mouse Monoclonal Antibody [clone: 7H11]

Supplier: Young In Frontier
The Notch signaling pathway is important for cell-cell communication, which involve gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. It critically influences cell proliferation, differentiation, and apoptosis in metazoans. The hairy and enhancer of split (HES) family is a basic helix-loop-helix (bHLH) type trancriptional repressor and acts as Notch effectors by negatively regulating expression of downstream target genes such as tissue-specific transcription factors. HES-1 is an upstream negative regulator of REST expression. Silencing of the transcriptional repressor REST is required for terminal differentiation of neuronal and β-cells.
Recent integrative genomic analyses on HES/HEY family suggest that HES1 and HES3 are target genes of the embryonic stem cell-specific network of transcription factors, and that HES1, HES5, HEY1, HEY2 and HEYL are target genes of Notch signaling pathway.

Western Blot: 1:500~1,000; Immunoprecipitation: 1 μl;

Type: Primary
Antigen: HES1
Clonality: Monoclonal
Clone: 7H11
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b
Reactivity: Human, Mouse, Rat



Expand All / Collapse All
Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL LF-MA0184 10219-188 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

Generate Barcodes Barcode Label Format: 
Generate PDF Catalog Page


Antigen Symbol HES1
Antigen Name Hairy and enhancer of split 1
Reactivity Human, Rat, Mouse
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone 7H11
Host Mouse
Isotype IgG2b
Western Blot Yes
ImmunoPrecipitation Yes
Antigen Synonyms Hairy-like, Transcription factor HES-1, HRY, Hairy and enhancer of split 1, HL, HHL, Hairy homolog
Cross Adsorption none
Immunogen His-tagged recombinant human Hes1 protein purified from E.coli
Purification Ammonium sulfate precipitation
Storage Temperature Store for 1 year at -20°C from date of shipment
Shipping Temperature Ice
Enter Details

Select the article for which you are looking for Certificate

Indicate the Lot Number. This field is mandatory.

Enter Certificate Details

Enter the Lot number:

Choose from recent batch/lot numbers:

Review & Compare Alternatives
We found alternative products that can save you up to  per item-unit.  To compare product details, select up to 3 alternatives below and click Compare Selected. To add items to your basket, enter a quantity and click Add to Basket.

Original Product:

Description Catalog Number Availability Unit Your Price Price Per Qty

A new look and a renewed commitment

Built on the features & resources you know, optimized with innovation from Avantor®. Our new brand symbolizes agility and our ability to adapt to customer needs.

Learn More Start Shopping