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Anti-HP Mouse Monoclonal Antibody [clone: 2F4]

Supplier: Young In Frontier
LF-MA0158
Haptoglobin (abbreviated as Hp) is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. Hp in its simplest form consists of two α- and two β-chains, connected by disulfide bridges. The chains originate from a common precursor protein which is proteolytically cleaved during protein synthesis. Hp exists in two allelic forms in the human population, so called Hp1 and Hp2; the latter one having arisen due to the partial duplication of Hp1 gene. Three phenotypes of Hp are found in humans: Hp1-1, Hp2-1, and Hp2-2. Hp phenotypes are associated with pathogenesis of a number of human disorders, such as diabetes, cardiovascular disease, etc. Hp plays a role in the host defence responses to infection and inflammation, acting as a natural antagonist for receptor-ligand activation of the immune system, also.

Western Blot: 0.5 μg/ml;

Type: Primary
Antigen: HP
Clonality: Monoclonal
Clone: 2F4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL LF-MA0158 10219-136 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol HP
Antigen Name Haptoglobin
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone 2F4
Host Mouse
Isotype IgG1
Western Blot Yes
ELISA Yes
Antigen Synonyms HPA1S, HP2-ALPHA-2, MGC111141, BP
Concentration 1 mg/ml
Cross Adsorption none
Immunogen Protein purified from Human plasma
Purification Protein G purified
Storage Temperature Store for 1 year at -20°C from date of shipment
Shipping Temperature Ice
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