Anti-HP Mouse Monoclonal Antibody [clone: 2F4]

Supplier: Young In Frontier
LF-MA0158
10219-136EA 413.6 USD
10219-136
Anti-HP Mouse Monoclonal Antibody [clone: 2F4]
Haptoglobin (abbreviated as Hp) is a protein in the blood plasma that binds free hemoglobin released from erythrocytes with high affinity and thereby inhibits its oxidative activity. Hp in its simplest form consists of two α- and two β-chains, connected by disulfide bridges. The chains originate from a common precursor protein which is proteolytically cleaved during protein synthesis. Hp exists in two allelic forms in the human population, so called Hp1 and Hp2; the latter one having arisen due to the partial duplication of Hp1 gene. Three phenotypes of Hp are found in humans: Hp1-1, Hp2-1, and Hp2-2. Hp phenotypes are associated with pathogenesis of a number of human disorders, such as diabetes, cardiovascular disease, etc. Hp plays a role in the host defence responses to infection and inflammation, acting as a natural antagonist for receptor-ligand activation of the immune system, also.

Western Blot: 0.5 ?g/ml;

Type: Primary
Antigen: HP
Clonality: Monoclonal
Clone: 2F4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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