Anti-Matriptase Mouse Monoclonal Antibody [clone: B12]

Supplier: Enzo Life Sciences
905-1007-0100
10049-274EA 619.28 USD
10049-274
Anti-Matriptase Mouse Monoclonal Antibody [clone: B12]
Antibodies
The protein encoded by the Matriptase gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis.

Type: Primary
Antigen: Matriptase
Clonality: Monoclonal
Clone: B12
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human
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