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Recombinant Human sTNF Receptor Type II (Carrier-free)

Supplier: Tonbo Biosciences
21-7084-U500 21-7084-U005 21-7084-U020 21-7084-U100
TNF receptor II (TNFRII or TNFRSF1B), along with the structurally related TNFRI, belong to the TNF receptor superfamily of proteins. TNFRII has a more restricted expression pattern than TNFRI, limited mainly to hematopoietic and immune system cells, whereas TNFRI is thought to be present on all cell types. TNFRII is a high-affinity receptor for TNF-alpha and also binds TNF-beta, but at a lower affinity. Binding to membrane-bound TNF results in effective activation, but while soluble TNF binds to TNFRII, it does not activate its signaling pathway. Signaling through this receptor regulates various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. The soluble form of TNFRII is capable of inhibiting TNF-alpha-induced activities by acting as a decoy receptor, thereby reducing the inflammatory response.

  • Carrier-free




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg 21-7084-U100 10002-424 Each (100µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

20 µg 21-7084-U020 10274-018 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

5 µg 21-7084-U005 10274-016 Each (5µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 µg 21-7084-U500 10274-020 Each (500µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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SPECIFICATIONS

Protein/Peptide Name Stnf R Type Ii STNF R TYPE II Stnf R Type Ii
Protein Synonyms TNFR80, p80, TNFRSF1B, CD120b, TNFR75, Soluble Tumor Necrosis Factor type II, p75
Protein/Peptide Type Recombinant
Species Human
Source E. coli
Protease-free Yes
Animal-Free Yes
Carrier-Free Yes
Purity 98%
Endotoxin Content <0.1ng/ug of protein
Storage Conditions −20 °C
Tested Applications Bioassay
Protein Type Recombinant
Reactivity Mouse
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