Human Recombinant PDGF-AA (from E. coli)

Supplier: Tonbo Biosciences
21-7080-U500 21-7080-U002 21-7080-U100 21-7080-U010
10273-982EA 2956.61 USD
10273-982 10002-416 10273-980 10273-978
Human Recombinant PDGF-AA (from E. coli)
Platelet-derived growth factor-AA (PDGF-AA) is one of the five dimeric proteins belonging to the PDGF family. Other members are homodimers PDGF-BB, PDGF-CC, PDGF-DD, and the heterodimer PDGF-AB. The PDGFs are produced by platelets, stored in platelet alpha-granules and are released upon platelet activation. PDGF proteins are generally considered as potent mitogens for connective tissue cells, and can also be chemotactic for fibroblasts, smooth muscle cells, neutrophils and mononuclear cells. PDGF-AA is well known as a potent mitogen for the proliferation of oligodendrocyte progenitor cells (OPCs). Two receptors have been identified for the PDGF proteins – PDGFR alpha and PDGFR beta. PDGF-AA binds to PDGFR alpha, but not PDGFR beta which appears to be specific for PDGF-BB and PDGF-AB.

  • Carrier-free
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