Anti-SELL Rat Monoclonal Antibody (redFluor® 710) [clone: MEL-14]

Supplier: Tonbo Biosciences
80-0621-U025 80-0621-U100
10208-534EA 171.51 USD
10208-534 10208-536
Anti-SELL Rat Monoclonal Antibody (redFluor® 710) [clone: MEL-14]
Antibodies
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.

The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.

Type: Primary
Antigen: SELL
Clonality: Monoclonal
Clone: MEL-14
Conjugation: redFluor® 710
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse
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