Ionomycin ≥90%

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

0215961101
IC15961101EA 220.81 USD
IC15961101
Ionomycin ≥90%
Ionomycin

Ionomycin is a highly selective calcium ionophore and a polyether antibiotic produced by Streptomyces conglobatus.


  • Clear gel


Ionomycin is a useful tool for increasing intracellular Ca2+ concentration


Ionomycin is a Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+. It induces apoptotic degeneration of embryonic cortical neurons, induces central demyelination and inhibits adrenal bovine TREK-1 channels.


It is also used to equilibrate intracellular and extracellular calcium ion levels for in situ calibrations of fluorescent indicators. It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochodrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.


Soluble in DMSO (25 mg/mL) and acetonitrile (10 mg/mL)

Formula: C₄₁H₇₂O₉
Storage Temperature: Freezer
MDL Number: MFCD06798385
CAS Number: 56092-81-01
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