ICNA02158056

0215805605 0215805625
IC15805625EA 325.98 USD
IC15805625 IC15805605
ICNA02158056
Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic. Flumequine is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It is used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance.

Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .

Practically insoluble in water, slightly soluble in ethanol, in methanol, acetone and in chloroform, insoluble in benzene, soluble in alkaline solution, soluble in 1M ammonium hydroxide (200 mg/ 4 mL-clear faint yellow solution).

Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic. Flumequine is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It is used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance.
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